Smiling woman touching her silky skin on studio background.Advertising Polynucleotide treatments at Rathfarnham Medical

Regenerate and revitalise your skin – Naturally

Polynucleotide treatment includes aesthetic injections that regenerate skin by stimulating collagen, elastin and fibroblasts to improve hydration, texture and firmness. It has minimal discomfort and visible results from about three weeks, lasting 6–9 months.

Areas Treated

Face, under eyes, neck and jawline

About the Treatment

A series of 3 treatments, 2-4 weeks apart in our Dublin clinic. Numbing cream is applied.

Costs

Single treatment: €300 + €70 initial consultation*
Introductory package deal: 3 initial treatments + 1 free maintenance treatment.

* Initial consultation fee is credited toward treatment if booked within 30 days.

What results to expect with Polynucleotide Treatment

Enhancing skin hydration, circulation and overall skin quality and rejuvenation of the under eyes, face and neck. The full benefits of polynucleotide rejuvenation tend to be seen several months after completing the treatment. Patients can expect to see initial results after three weeks, which will last six to nine months.

Specific results for each area:

Under Eyes: reduce dark under-eye circles and smooth crow’s feet, fine lines, hollows and puffiness beneath the eyes.

Forehead: Polynucleotides smooth fine lines, encourage glowing skin and can be used as an alternative to popular antiwrinkle injections.

Cheeks: Polynucleotides smooth folds and lines, tightening and lifting cheeks and hydrating skin.

Smokers lines and lines around the mouth/chin: Polynucleotides smooth lines around the mouth without plumping or adding volume.

Jawline: Polynucleotides help tighten and define jawline.

Neck: Treat crepey-looking skin and fine lines on the neck.

Polynucleotides Under Eyes

Polynucleotides under eyes are an increasingly popular treatment for dark circles, fine lines and crepey skin. By stimulating collagen production, improving hydration and supporting tissue repair, they help create brighter, smoother and healthier-looking skin beneath the eyes.

Polynucleotides for Dark Circles

Dark circles can be caused by ageing, thinning skin, genetics or lifestyle factors. While polynucleotides cannot treat every type of dark circle, they can improve skin quality, hydration and elasticity, helping the under-eye area appear brighter, healthier and more refreshed over time.

Polynucleotides for Crepey Under Eye Skin

Crepey under eye skin develops as collagen and elastin levels decrease with age, causing the skin to appear thin, fragile and wrinkled. Polynucleotide treatment helps stimulate collagen production and improve skin elasticity, creating smoother, firmer and healthier-looking skin beneath the eyes.

Polynucleotides for Fine Lines and Wrinkles

Fine lines around the eyes are a common sign of ageing and can become more noticeable as skin loses hydration and elasticity. Polynucleotides support skin regeneration and hydration, helping to soften fine lines, improve skin texture and deliver gradual, natural-looking rejuvenation.

FAQ’s about Polynucleotide Treatment in Dublin

Is Polynucleotide Treatment painful?

Most patients find polynucleotide treatment very comfortable. A topical numbing cream is applied beforehand, and the procedure uses ultra-fine needles to minimise discomfort. In most cases, the treatment is very well tolerated with only mild sensitivity.

How long does the Polynucleotide treatment take?

A typical course of polynucleotide treatment involves 2–3 sessions spaced 2–4 weeks apart. To maintain results, a top-up treatment is usually recommended every 6–12 months, depending on your skin condition and goals.

What are Polynucleotides ?

Polynucleotides are highly purified, naturally derived DNA fragments typically extracted from fish sources. In aesthetic treatments such as polynucleotide treatment in Dublin clinics, they are used to support skin repair, hydration, and regeneration.

How do Polynucleotides work?

Polynucleotide treatment works by stimulating the skin’s natural repair processes. Unlike dermal fillers that add volume or anti-wrinkle injections that relax muscles, polynucleotides under eyes and other areas work by improving skin quality from within. They help boost hydration, elasticity, and overall skin texture over time for natural-looking rejuvenation.

What is the difference between Polynucleotides & skin boosters?

While both treatments improve hydration, polynucleotide treatment goes deeper by stimulating fibroblasts, collagen, and elastin production. This makes polynucleotides more regenerative, offering longer-lasting improvements in skin quality compared to traditional skin boosters.

Are there any side effects to polynucleotides injections?

After polynucleotide treatment, mild swelling, redness, or small raised blebs at the injection site are common and usually settle within a few days. Bruising can occasionally occur but can be reduced with arnica. Polynucleotides are highly biocompatible and widely considered safe and well tolerated.

Can polynucleotides help with dark circles?

Yes. Polynucleotides under eyes can improve the appearance of dark circles, particularly when caused by thin, dehydrated, or ageing skin. By enhancing skin thickness and hydration, the under-eye area can appear brighter and more refreshed.

Do polynucleotides work for under eye wrinkles?

Yes, polynucleotides under eyes can help soften fine lines and crepey skin. The treatment works by stimulating collagen production and improving overall skin quality, with gradual, natural-looking results over time.

How many polynucleotide treatments are needed under the eyes?

For optimal results with polynucleotides under eyes, most patients require a course of 2–3 treatments spaced a few weeks apart. Maintenance treatments are often recommended every 6–12 months to sustain improvements.

How long do polynucleotide under eye results last?

Results from polynucleotide treatment typically last between 6 and 12 months. Duration depends on factors such as age, lifestyle, skin quality, and whether maintenance sessions are completed.

Are polynucleotides safe for the under eye area?

Yes. Polynucleotides under eyes are considered very safe when administered by a qualified medical professional. They are especially suitable for delicate areas like the under-eye region due to their regenerative and biocompatible properties.

Can I use Polynucleotides alongside other treatments?

Yes. Polynucleotide treatment can be used on its own or combined with other aesthetic treatments as part of a personalised skin rejuvenation plan, including in clinics offering polynucleotide treatment in Dublin and beyond.

Schedule a consultation with our doctor

Polynucleotide Treatment for Under Eyes & Skin Rejuvenation