Smiling woman touching her silky skin on studio background.Advertising Polynucleotide treatments at Rathfarnham Medical

Regenerate and revitalise your skin – Naturally

Polynucleotide treatment includes aesthetic injections that regenerate skin by stimulating collagen, elastin and fibroblasts to improve hydration, texture and firmness. It has minimal discomfort and visible results from about three weeks, lasting 6–9 months.

Areas Treated

Face, eyes, neck and jawline

About the Treatment

A series of 3 treatments, 2-4 weeks apart. Numbing cream is applied.

Costs

Single treatment: €300 + €70 initial consultation*
Introductory package deal: 3 initial treatments + 1 free maintenance treatment.

* Initial consultation fee is credited toward treatment if booked within 30 days.

What results to expect with Polynucleotide Treatment

Enhancing skin hydration, circulation and overall skin quality and rejuvenation of the under eyes, face and neck. The full benefits of polynucleotide rejuvenation tend to be seen several months after completing the treatment. Patients can expect to see initial results after three weeks, which will last six to nine months.

Specific results for each area:

Eyes: reduce dark under-eye circles and smooth crow’s feet, fine lines, hollows and puffiness beneath the eyes.

Forehead: Polynucleotides smooth fine lines, encourage glowing skin and can be used as an alternative to popular antiwrinkle injections.

Cheeks: Polynucleotides smooth folds and lines, tightening and lifting cheeks and hydrating skin.

Smokers lines and lines around the mouth/chin: Polynucleotides smooth lines around the mouth without plumping or adding volume.

Jawline: Polynucleotides help tighten and define jawline.

Neck: Treat crepey-looking skin and fine lines on the neck.

FAQ about Polynucleotide treatment

Is Polynucleotide Treatment painful?

Most patients report minimal discomfort during the procedure. A topical numbing cream is applied before treatment, and very fine needles are used, making the injections well tolerated.

How long does the Polynucleotide treatment take?

Normally, your polynucleotide treatment will be performed every 2-4 weeks; 3 treatments in total. A single top-up treatment every 6-12 months is advised to sustain your results.

What are Polynucleotides ?

Polynucleotides are natural, highly purified DNA molecules usually extracted from the gonads of fish.

How do Polynucleotides work?

Polynucleotide treatments are regenerative rather than corrective. Unlike fillers, which add volume, or anti-wrinkle injections, which relax facial muscles, injectable polynucleotides work by repairing and rejuvenating the skin from within. They improve skin hydration, elasticity, and texture over time, delivering natural and gradual results.

What is the difference between Polynucleotides & skin boosters?

Both boosters and polynucleotide improve skin hydration, but polynucleotides regenerate skin cells at a deeper level, stimulating collagen, fibroblasts & elastin for longer lasting results.

Are there any side effects to polynucleotides injections?

Immediately after the procedure, you may notice some swelling and redness with bleb formation, which may develop into bruising over the coming days.  Arnica tablets or cream can help reduce any bruising which does occur. Polynucleotides are highly biocompatible and non-immunogenic, meaning they are safe and well tolerated by the body.

Can I use Polynucleotides alongside other treatments?

Yes, polynucleotides can be offered as a stand-alone treatment or used in combination with other procedures.

Schedule a consultation with our doctor

Polynucleotide Treatment